GenomeComp is a DNA sequence comparison tool and graphical user interface (GUI) viewer implemented in Perl/Tk. It can read one, two or three input sequences in either of FASTA, GENBANK or EMBL format, then it runs the external program BLASTN or MegaBlast to do the comparison between paired sequences in background. If the results already exist, it can skip that step and read the output file directly. Then the dynamic display of the results will show in the canvas of the main window.
GenomeComp can easily manage genome wide sequences (about several mega base pairs), so as to locate the rearrangements, insertions or deletions of genome segments between species or strains. In addition, it can show other features like repeat sequence distribution in one whole-genome sequence by self-comprison.
中科院生物物理所生物信息實驗室推出的可視化的微生物基因組比較工具。它可以接受FASTA、GenBank或EMBL等多種輸入數(shù)據(jù)格式，自動在后臺調(diào)用BLAST包中的核酸序列比較軟件進行比較操作，然后對結(jié)果進行分析和處理，過濾掉冗余的信息，最終將結(jié)果以動態(tài)的圖形化方式顯示出來。此軟件特別適用于比較具有較近親緣關(guān)系的物種或同一物種的不同株的基因組，可以很容易的發(fā)現(xiàn)出它們之間在基因組水平的變異，如插入、缺失或轉(zhuǎn)置等等。源代碼，130K。使用手冊（英文版），400K。
