Multiple Alignment Construction & Analysis Workbench (MACAW) is a program for locating, analyzing, and editing blocks of localized sequence similarity among multiple sequences and linking them into a multiple alignment. It includes sequence alignment search, editing and display. It is a very nice program according to many, allowing one to look for blocks of homology in sequences.
MACAW(Multiple Alignment Construction and Analysis Workbench)可以使用戶通過定位,分析，編輯及將比對(duì)序列片段聯(lián)合成塊)來構(gòu)建多重比對(duì).
MACAW整合了幾個(gè)新特性:
(1)使用新的搜索算法來定位局部相似區(qū)域,這避免了以前的技術(shù)所帶來的許多限制;
(2)使用最新發(fā)展的數(shù)學(xué)理論來評(píng)估塊相似性的統(tǒng)計(jì)學(xué)意義;
(3)使用多種 可視化工具對(duì)候選塊進(jìn)行評(píng)估以預(yù)測(cè)其包含于多重序列比對(duì)中的潛在可能性;
(4)有一個(gè)用戶界面允許用戶對(duì)塊進(jìn)行逐個(gè)編，用戶可以移 動(dòng)塊邊界,剔除特定片段或?qū)K鏈 接起來以形成復(fù)合多重比對(duì).
MACAW將可變編輯，分析 及顯示工具同一個(gè)簡(jiǎn)單但是強(qiáng)大的算法整合在一起，從而將比對(duì)分解成易解決的問題.
MACAW-hp.zip MACAW 2.05的中文使用說明。
